Chelsea interim manager Guus Hiddink is without Diego Costa for Monday's trip to Old Trafford after the striker picked up a suspension in the 2-2 draw against Watford.
Hiddink has also spoken of his belief that Radamel Falcao lacks match fitness, so Loic Remy is likely to start in Costa’s absence.
Eden Hazard and Jon Obi Mikel came on as substitutes against Watford so are in contention to start — possibly at the expense of Cesc Fabregas, who came off at half-time.
Bournemouth manager Eddie Howe will make a late decision on whether to include Harry Arter in the squad for their Barclays Premier League clash against Arsenal, also on Monday.
Arter was brought off at half-time in the Boxing Day goalless draw with Crystal Palace after he picked up an early yellow card and Howe said it was to “manage his workload” after recovering from a hamstring injury picked up at the end of November.
Meanwhile Arsene Wenger is confident Arsenal will numb the pain of the Boxing Day shellacking at Southampton within 48 hours.
The trip to St Mary’s seemingly offered the Frenchman’s side a great chance to go top of the Barclays Premier League, but a poor display saw them return to north London reeling from a shock 4-0 defeat.
Shane Long’s brace complemented an exceptional Cuco Martina half-volley and Jose Fonte’s header as Saints ended a six-match winless run in some style.
There is little time for Arsenal to wallow, though, as the hectic festive period means they take on another south-coast side on Monday.
Bournemouth will look to ratchet up the pressure, but Wenger is confident of a positive response at the Emirates Stadium.
“I believe what I say to my players is between my players and myself,” he said after the 4-0 hammering at St Mary’s.
“These players have fantastic spirit and they can show that in 48 hours.
“We are in a job where we have to respond. We want to respond from disappointments.
“Unfortunately, there’s no possible career without disappointment. Nobody, not even the best players in the world, can have that.”
The Gunners boss also downplayed speculation linking Arsenal to Basle’s Mohamed Elneny and was keen to underline the quality waiting that will be at his disposal after injury.
“That’s always the question you get,” Wenger said. “We have many players who are injured and will come back soon.
“Buy, buy, buy, buy is always the solution that people see.
“I think it’s true that we couldn’t score, but we conceded goals (against Southampton) and we have enough defenders.”