World’s first gene-editing therapy for humans approved in UK
Treatment offers relief and possibly a cure for patients with sickle cell disease and one other blood ailment
Vertex
Cystic fibrosis drug group Vertex sees 26% jump in revenues at Irish unit
Sales of Kaftrio driving group at US pharmaceutical group which specialises in Ireland’s most common life-threatening inherited disease
New medicines must be affordable to all, Minister tells drug companies
Stephen Donnelly tells pharma conference government and industry need to work closer together to improve patient access
Cystic fibrosis drug at centre of HSE row behind sales surge at drugmaker
Revenues at Vertex Pharmaceutical rose to $1.55bn last year, driven mainly by Kaftrio sales
Fexco slid into €48m loss in 2020 as Covid hit foreign exchange
Financial services company said it returned operating profit in fourth quarter this year
‘It’s like a miracle’: The man who may be the first person cured of type 1 diabetes
Brian Shelton’s life was ruled by his disease, until a new treatment gave hope to him and millions of others
Dublin biotech firm Nuritas eyes global expansion with $45m funding round
Early backers include U2’s Bono and The Edge and Salesforce chief Marc Benioff
Irish arm of Orkambi maker sees pre-tax profits rise to €5.4m
2020 was first year all sales to Vertex entities in EU were fulfilled by Vertex Ireland
Fexco dynasty enjoys further success as Taxamo sold in $200m deal
Co Kerry fintech led by John McCarthy is being acquired by US company Vertex
After decades of fundraising and research, could the end of Cystic Fibrosis be in sight?
Drugs are available to treat 95% of patients, but access is still a problem for some
European shares sink on lockdown concerns as virus cases surge
Run of negative news drags European bourses into red
Cystic fibrosis drug group puts €250,000 into Barretstown camp
Vertex Pharma donation will fund holiday camp for up to 125 children
HSE agrees to reimburse cost of new cystic fibrosis treatment
Trikafta to be available to patients aged 12 and over once it receives European approval
Cystic fibrosis drug could make disease a manageable condition
Improvement in lung function of patients treated with Trikafta described as ‘striking’
Cystic fibrosis drug drives surge in sales at Vertex Pharmaceuticals
Breakthrough medicine Orkambi main factor behind 71% rise in sales
Five Feet Apart: ‘As a person with Cystic Fibrosis I'd encourage everyone to see it’
‘As a community we need to use Five Feet Apart as a lever to highlight the situation’
Seventy children with cystic fibrosis to benefit from new drug
Orkambi will be provided to Irish two to five-year-olds following deal with EU Commission
Big pharma’s usefulness a bitter pill for some to swallow
Success of pharma giants relies on quality of research and ability to develop new drugs
Oil stocks and online supermarket Ocado buoy European equities
In Dublin, Paddypower still goes up despite UK’s restrictions on betting terminals
Taoiseach wants cystic fibrosis treatment to be ‘best in world’
Ireland has the highest per capita rate of CF in the world due to particular gene pool
Orkambi access extended to younger children
Cystic fibrosis treatment had only been available to people aged 12 and over
A month-by-month look back at 2017 in Ireland
News review of the year: Border issues, the Garda whistleblower scandal, property prices, the Paradise Papers, Storm Ophelia and the Rescue 116 tragedy were some of the big stories of 2017
The major business events coming up in the week ahead
For your Diary: Ryanair, McDonald’s and the banks to reveal trading figures
World stocks buoyed by positive corporate earnings
In Dublin, INM shares take a hammering after company issues profit warning
Praise for campaigners as Orkambi deal agreed with HSE
Up to 600 people with cystic fibrosis will now be able to access life-saving drugs
Huge cost of Orkambi deal will be major challenge for HSE
Decision by Government will be welcomed by the country’s 600 cystic fibrosis patients
Cystic fibrosis drugs deal hailed as ‘massive victory’
Agreement testament to hard work of Cystic Fibrosis Ireland and patients, says Martin
HSE in last-ditch talks to secure cystic fibrosis drug
Executive to meet Orkambi maker in bid to secure deal estimated to cost over €250m
Markets edge up as UK triggers formal Brexit process
Euro slips after Reuters report on wariness of European Central Bank policymakers
Orkambi drug firm ‘perplexed’ by Government delays
Cystic Fibrosis Ireland concerned about lack of contact between HSE and Vertex
Cystic fibrosis patients defy Harris with Orkambi protest
Hundreds demonstrate outside Dáil in support of free access to groundbreaking drug
Taoiseach expects deal on CF drug Orkambi in coming weeks
HSE and manufacturer of costly medicine in ‘critical phase’ of discussions on deal
CF group claims new data supports case for Orkambi approval
Cystic Fibrosis Ireland warns of ‘strong outcry’ if HSE fails to approve Orkambi on cost
HSE fails to agree price for cystic fibrosis drug Orkambi
Health body indiciated it would pay up to €75m a year for product estimated to cost €400m
Orkambi-maker among sponsors of CF Ireland’s conference
US pharma Vertex in talks with HSE to reduce high price of cystic fibrosis drug
Update on Cystic Fibrosis drug Orkambi expected in new year
Negotiations with manufacturer ongoing as Harris accuses Vertex of trying to ‘extort’ taxpayers
Germany to provide free access to Orkambi cystic fibrosis drug
About 2,000 German patients to benefit as State continues to negotiate over price
HSE chief not optimistic on reaching price deal for Orkambi
Minister says he will not be bullied, as talks with pharma firm on cystic fibrosis drug reopen
Orkambi protests highlight need for clear policy on expensive drugs
Health spending in one area cannot come at expense of another
Harris challenges Orkambi firm to ‘stop spinning’ and get on with price talks
Government and Vertex differ over approach to price talks for cystic fibrosis treatment
HSE to resume talks on ‘exorbitant’ price of CF drug Orkambi
Vertex Pharmaceuticals wants Minister Simon Harris to take a role in negotiations
Orkambi company charge ‘grossly excessive’
Taoiseach calls in Dáil for resumed talks on cost of cystic fibrosis drug
Minister refuses to negotiate directly over cost of CF treatment
Drug company calls on Simon Harris to intervene after HSE rules out use of Orkambi
HSE seems set to reject ‘ground-breaking’ cystic fibrosis drug
Orkambi had been ‘considered unjustifiably expensive and not sufficiently cost effective’
Child patients will not receive cystic fibrosis drug due to cost
Study finds the use of the ‘wonder drug’ would cost €21m over a five-year period
Cystic fibrosis campaigners push for Orkambi funding
#YesOrkambi drive launched in support of approval for €160,000 per patient medicine
Minister proposes EU bulk buying of drugs to lower costs
Health authorities criticised for refusing to fund ‘game-changing’ cystic fibrosis drug
Cystic fibrosis patients dismayed as Orkambi rejected
CF campaigner Orla Tinsley says decision disappointing as trials showed drug works
Cystic Fibrosis drug Orkambi rejected as not cost effective
Price talks urged between Government and maker on €160,000 per patient medicine
Iseq stalls as the UK and US look to earnings season
International markets look ahead to upcoming batch of corporate earnings
Cystic fibrosis drug may be made available to patients
Orkambi has been described as a ‘game changer’ by health campaigners
Rise in bank stocks caps off biggest quarterly advance since 2009
Dublin’s Iseq underperforms rivals as heavyweights drag index down
New battery is ‘killer app’ for electric cars
Experts say new battery is a game-changer, tripling the driving range of current electric vehicles while also significantly lowering the costs
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